20 Best Inositol Benefits, Uses & Supplement Ingredient Pairings
Explore 20 benefits of Inositol as a supplement for PCOS, mental health, and metabolic health, and learn the best habits to enhance inositol supplementation.
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Nicotinamide Riboside, or NR for short, is a form of vitamin B3. It’s found in tiny amounts in some foods and is used by our bodies to help turn food into energy.
NR is special because it also helps our cells work better. It does this by boosting a substance in our cells called NAD+, which is super important for many cell functions.
Scientists are studying NR because it might help keep our bodies healthy as we get older. It’s not just a simple vitamin; it has the potential to support our cells in ways we’re just beginning to understand.
Nicotinamide Riboside (NR) is believed to enhance cellular health by boosting NAD+ levels, a vital molecule that declines with age. Higher NAD+ levels support cellular repair processes, which may contribute to the maintenance of healthy cells throughout the body.
NR supplementation could potentially delay cellular aging by promoting the activity of sirtuins, a group of proteins linked to longevity.
NR plays a role in energy metabolism by helping convert food into energy. This process is crucial for maintaining the health and function of our muscles and organs. By increasing NAD+ levels, NR ensures that our cells have the energy they need to perform their functions effectively, which may be beneficial for individuals looking to optimize their physical performance or combat fatigue.
The brain is a high-energy demanding organ, and NR might support cognitive health by fostering the production of NAD+. Adequate NAD+ levels are essential for maintaining neuronal health and function, which could translate to improved memory and cognitive functions.
NR’s potential neuroprotective effects are of particular interest in the context of age-related cognitive decline.
Heart health may benefit from NR supplementation due to its role in cellular metabolism and repair. By boosting NAD+ levels, NR supports the health of blood vessels and heart muscle cells. This support could help maintain cardiovascular function, which is especially important as we age and our risk for heart-related issues increases.
While NR is generally considered safe, the specific nicotinamide riboside dosage and its effects can vary depending on age and individual health status. Younger individuals may require less NR, while older adults could benefit from higher doses due to the natural decline in NAD+ levels.
It’s important to consult a healthcare provider to determine the appropriate dosage. Always check with your primary care provider before making any changes to your supplements.
Combining Nicotinamide Riboside (NR) with other supplement ingredients can enhance its benefits. Popular pairings include NR with resveratrol, pterostilbene, and quercetin, which are often chosen for their synergistic effects on cellular health and aging. Other common combinations involve pairing NR with omega-3 fatty acids, curcumin, and green tea extract, targeting overall wellness and anti-inflammatory properties. These combinations are ranked based on their widespread use and potential to address notable health concerns.
Resveratrol, a compound found in red wine, is often combined with NR to amplify anti-aging effects. Resveratrol activates sirtuins, which work synergistically with the NAD+ produced from NR to enhance cellular repair and longevity. This combination is particularly popular among those looking to support cardiovascular health and slow aging processes. However, it’s important to note that pregnant women should avoid high doses of resveratrol, and interactions with blood-thinning medications should be considered.
Pterostilbene, similar to resveratrol but with potentially better bioavailability, is another favorite pairing with NR. This duo is thought to support cognitive function and brain health, with pterostilbene providing antioxidant benefits that complement the NAD+ boosting properties of NR. While generally safe, it’s wise to consult a healthcare provider before combining these supplements, especially for those on cholesterol-lowering drugs, as pterostilbene may have similar effects.
Quercetin, a flavonoid with anti-inflammatory properties, is often taken with NR to combat oxidative stress and support immune health. The combination is believed to enhance the body’s defense mechanisms against cellular damage and support healthy aging. Quercetin can also influence how certain medications are metabolized, so individuals taking prescription drugs should seek medical advice before starting this supplement regimen.
Nicotinamide riboside is a supplement that’s caught the attention of many health experts. It’s known for its potential to boost energy, support healthy aging, and improve brain health. Some health providers have even written books about it. Let’s look at what they have to say.
Dr. David Sinclair, a professor of genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, is a leading expert on aging. In his book Lifespan: Why We Age—and Why We Don’t Have To, he discusses the role of NAD+ in aging and how nicotinamide riboside can help maintain NAD+ levels. He believes that boosting NAD+ can help slow down the aging process.
Dr. Rhonda Patrick, who runs a popular health podcast, often discusses the importance of cellular metabolism and the impact of NAD+ on cellular function. She has highlighted nicotinamide riboside as a supplement that can support mitochondrial health, which is crucial for energy production in the body.
Dr. Peter Attia is known for his focus on the science of longevity. He explores strategies for extending life and improving the quality of life, including the use of supplements like nicotinamide riboside. Through his podcast and various interviews, he has discussed how maintaining NAD+ levels is vital for metabolic health and longevity.
Dr. Joseph Mercola, a well-known alternative medicine proponent, has written extensively about the ketogenic diet and metabolic health. In his work, he has mentioned the benefits of nicotinamide riboside in supporting metabolism and energy levels, especially in the context of a low-carb, high-fat diet.
Dr. Brenna Hill, a naturopathic doctor with a focus on cognitive health, recommends nicotinamide riboside for its potential to protect neurons and support brain function. She cites studies that suggest NR might help improve memory and cognitive ability, especially in older adults.
To maximize the benefits of nicotinamide riboside, incorporating certain lifestyle habits can be crucial. Here’s a list of activities that are synergistic with its use:
Nicotinamide Riboside (NR) is generally considered safe and well-tolerated. However, as with any supplement, there can be side effects, although they are typically mild.
Some individuals may experience mild to moderate side effects such as nausea, fatigue, headaches, diarrhea, stomach discomfort, or indigestion. These side effects are not common and often resolve on their own.
There have been rare reports of more significant effects, such as flushing or changes in blood sugar levels. Individuals with diabetes or those on blood sugar-lowering medications should monitor their blood sugar closely when taking NR.
If you notice any unusual symptoms after starting NR, such as a rash or dizziness, it’s important to stop taking the supplement and consult a healthcare provider. It’s also advisable to start with a lower dose of NR to assess tolerance before increasing to the recommended dosage.
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